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Magnetic Beads for Bio Application Ceramic Beads for Bio Application
Micro-patterned Injection-molded Chips

Magnetic Beads for Bio Applications

Maxell’s 0.25μm magnetic beads facilitate high-sensitivity,
short-time measurements

The product and/or technology on this web page is under development. Commercialization is yet to be determined.

Maxell’s magnetic beads for biological applications have been developed using magnetic particle processing and surface treatment technologies that were developed in tandem with Maxell’s magnetic tape products. Compared with other commercial magnetic beads, Maxell’s submicron magnetic beads offer a host of benefits, including high magnetic gathering speeds and superior redispersion. Let Maxell’s nanotechnologies support you in the field of biochemical research and development.




Features

Small size
  • Maxell has developed magnetic beads with a particle size of about 0.25µm. In spite of the small size, the beads have excellent magnetic properties. Beads with a particle size of less than 0.1µm are also available for use as magnetic tags.
High-speed magnetic gathering and redispersion
  • Direct surface treatment on ferrite particles achieves a high iron content and improves magnetic gathering speeds. Maxell’s proprietary surface treatment realizes superior redispersion after magnetic gathering.
Surface modifications for bio applications
  • Maxell’s standard magnetic beads have been coated with a carboxyl group to enable antibodies, enzymes and nucleic acids to adhere to the surface of the beads.
  • Please contact us to find out about other functional group coatings.
Suitable for a range of applications
  • By immobilizing DNA, antibodies, etc., to the surface of the beads, various biochemicals can be captured specifically.
  • The magnetic bead - target biochemicals can be collected using an external magnet. Leftover materials can be easily removed by washing. Consequently, it is possible to purify any sample through extraction of target biochemicals. It is also possible to detect a target biochemical by the fluorescent labeling of the target materials.
  • Nanometer-size magnetic beads can also be used as magnetic sensing markers.

Comparison of Maxell submicron beads with other commercial beads
 

Particle size

Specific surface area Magnetic gathering Iron content Functional group
Maxell beads ca. 0.25µm ca. 7m2/g(35m2/cm3) Excellent ca. 70% Carboxyl group
Other commercial beads ca. 3µm 2-8m2/g(3-12m2/cm3) Good ca. 15% Carboxyl group, streptavidin, and others


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Principle of magnetic gathering





High-speed magnetic gathering

Maxell’s submicron beads increase their surface areas. Their iron content also increases, by around 70%. As a result, magnetic gathering time is shortened. Maxell beads help improve the efficiency and automation of inspections and analyses.



Superior dispersion and redispersion

Thanks to Maxell’s proprietary bead surface treatment technology, Maxell’s submicron beads have relatively weak magnetic cohesion that allows them to disperse into a solution faster than other manufactured beads once magnetic gathering and removal of leftover materials is complete. As well as their high-speed magnetic gathering properties, Maxell beads help improve the efficiency and automation of inspections and analyses.


Applications

●Protein purification  ●Nucleic acid purification
●Cell separation  ●Microorganism separation
●In vitro diagnostics, food inspection, environmental evaluation, etc.


Numerical values described herein are examples of measured values and are not necessarily correct.
All features and specifications are subject to change without notice.


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