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The products and/or technologies on this webpage are still under development; so the commercialization of them is yet to be determined. |
Submicron size with diameters of about 0.25 μm;
realizing high magnetic gathering speeds and
superior redispersion properties |
| Maxell’s magnetic beads for biological applications have been developed using magnetic particle
processing and surface treatment technologies that were developed in tandem with Maxell’s
magnetic tape products. Maxell’s submicron magnetic beads offer a host of benefits, including high
magnetic gathering speeds and superior redispersion, and have the potential to realize
high-sensitivity, short-time measurements. Let Maxell’s nanotechnologies support you in the field of
biochemical research and development. |
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Small-size beads
- Maxell has developed magnetic beads with a particle size of
about 0.25 μm.
- Reduction of bead size increases surface area and number of
particles per volume, potentially improving detection sensitivity
and reaction rate.
High-speed magnetic gathering
- High iron content of approximately 70 % achieved by direct surface
treatment on ferrite particles improves magnetic gathering speeds.
Superior redispersion
- Maxell’s proprietary surface treatment realizes low bead
aggregation and offers superior redispersion after magnetic
gathering.
Surface modifications for bio applications
- Maxell’s standard magnetic beads are coated with carboxyl
groups. Biological materials such as antibodies, enzymes and
nucleic acids can be attached. Streptavidin-coated beads are
under development.
Suitable for a range of applications
- By immobilizing DNA, antibodies, etc., on the surface of the
beads, various biochemicals can be specifically captured.
- Once target biochemicals have adhered to the magnetic
beads, the beads can be collected with an external magnet.
Leftover material that has not adhered to the beads and
remains in the solution can be easily removed with washing.
Maxell’s magnetic beads offer effective extraction,
purification and detection of target materials.
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When bead size is reduced, the specific surface area
increases but magnetic gathering speed usually
decreases. However, Maxell has reduced the
magnetic gathering time of submicron magnetic beads
by increasing the bead iron content to approximately
70 %. Maxell’ s beads help improve the efficiency and
automation of inspections and analyses. |
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Thanks to Maxell’ s proprietary bead surface
treatment technology, submicron bead aggregation
is relatively low, allowing the beads to disperse into
a solution once magnetic gathering and removal of
leftover materials is complete. As well as their
high-speed magnetic gathering properties, Maxell
beads help improve the efficiency and automation
of inspections and analyses. |
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Solution color change can be realized with a
small number of Maxell’ s submicron beads to
which an enzyme is attached. Materials, such as
antibodies, bound directly or via immobilized
streptavidin to carboxyl groups on the surface of
the beads can potentially be used to detect
minute amounts of target materials. |
[ Measuring method ]
Absorbance has been measured as color change using magnetic beads to which biotinylated enzyme (peroxidase) was attached via streptavidin attached to carboxyl groups. |
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- Applications
Extraction, purification and detections of antigens,
proteins, nucleic acids,
separation of cells and microorganisms, etc.
- Application fields
Biological research and development,
in vitro diagnostics, food inspections,
environmental evaluations, etc.
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