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The products and/or technologies on this webpage are still under development; so the commercialization of them is yet to be determined. |
High-specific-gravity ceramic beads
with diameters of 20 μm – 1 mm;
truly spherical and uniform in size |
| Maxell’s ceramic beads for biological applications have been developed using small-particle
processing technology that was developed in tandem with Maxell’s tape products. Maxell’s ceramic
beads have many attractive features, including true spherical shape, narrow particle size distribution,
high specific gravity and chemically stable properties. Maxell offers a wide range of particle sizes up
to approximately 1 mm. Let Maxell’s nanotechnologies support you in the field of biochemical
research and development. |
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Ceramic substrate with high specific gravity
- Beads with chemically stable ceramic substrates have high
specific gravities and therefore can be easily settled, stirred,
moved and arranged using gravity.
True spherical shape
- Maxell’s ceramic beads are characterized by their true spherical
shape. The average ratio of the longest and shortest radius of a
20-μm bead is 1.07*1.
*1 Measured in image captured by optical microscope
Narrow particle size distribution
- Maxell offers uniformly-sized ceramic beads with narrow particle
size distribution.
- Maxell’s standard ceramic bead sizes are 20 μm and 1 mm.
Excellent surface binding capacity
- Maxell’s special surface treatment of its ceramic beads increases
the number of surface binding points. As a result, binding of and
reaction with target materials have been improved.
- The ceramic beads can be coated with avidin to enable binding
of antibodies and nucleic acid. More than 1010 biotinylated oligo
DNA (60-mer) per mm2 can be bound assuming that the bead
surface is smooth.
Suitable for a range of applications
- By adhering DNA, antibodies, etc, to the surface of the beads,
various biochemicals can be collected specifically or made to react.
- Maxell’s ceramic beads have large particle sizes, thereby
allowing for multi-sample, multi-analysis detection such as bead
array or massively parallel processing.
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Maxell offers ceramic beads with uniform sizes.
The coefficient of variation (CV)*2 of particle
size is low even with small ceramic beads— approximately 4 % with 20-µm beads. CV
decreases further with larger beads.
*2 CV is the ratio of the particle size distribution standard
deviation to the particle size average.
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Because of their high specific gravity
compared with resin-substrate beads,
ceramic beads can be easily settled, stirred,
moved and arranged using only gravity.
The beads can be placed in small wells
without centrifugation by rolling them using a
liquid current, and can be moved without the
use of a pump by tilting the container. With
these features, ceramic beads have the
potential for a variety of applications such as
use in microchips.
Micro injection-molded chip
Bead array chips are manufactured using a micro injection molding technique and a stamping technique developed for the
manufacture of optical discs such as CDs and DVDs.
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- Applications
Detection or reaction of biological materials, etc.
- Application fields
Biological research and development, in vitro diagnostics,
food inspections, environmental evaluations, etc.
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